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SCIENCE
NeuroDex and Stanford Researchers Publish First Evidence of CNS Target Engagement for GLP-1 and PPARγ Agonists Using Blood-Based Neuron-Derived Extracellular Vesicles - BioSpace
NeuroDex and Stanford researchers showed that GLP-1 drugs (weight-loss medicines) reach the brain and affect it. They used a new blood test with tiny particles from nerve cells to measure this effect for the first time.
Analysis
A new blood test can show if GLP-1 drugs reach the brain. This could help prove how weight-loss drugs work and speed up testing of new ones.
- NeuroDex and Stanford published first evidence of CNS target engagement for GLP-1 drugs
- Test uses neuron-derived extracellular vesicles drawn from blood
- Method also covers PPARγ agonists
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