WATCHLONGEVITY

Sunday, June 21, 2026

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COMMERCIAL · PRIMARY SOURCE

Zepbound (tirzepatide) and Shaquille O'Neal launch national campaign after NBA legend learns the obstructive sleep apnea he has lived with for years is treatable

Eli Lilly and basketball star Shaquille O'Neal launched a marketing campaign called Watch This to talk about obstructive sleep apnea (a breathing problem during sleep). Zepbound (tirzepatide) is now approved as the first drug for this condition in adults who also have obesity.

Analysis

Lilly is pushing Zepbound into a new patient group — people with sleep apnea and obesity. A celebrity campaign can drive awareness and new prescriptions.

  • Eli Lilly launched a marketing campaign called 'Watch This' featuring Shaquille O'Neal
  • Zepbound (tirzepatide) is approved as the first drug for obstructive sleep apnea in adults with obesity
  • O'Neal said he had lived with obstructive sleep apnea for years before learning it was treatable
Eli Lilly Press Releases10d
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DEVELOPING
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CLINICAL TRIAL · PRIMARY SOURCE2 outlets

Lilly's oral GLP-1 Foundayo (orforglipron) delivered superior A1C control and weight loss in three pivotal type 2 diabetes trials

Eli Lilly's pill version of orforglipron (Foundayo) beat Novo Nordisk's semaglutide pill at lowering blood sugar and weight loss in three large diabetes trials. Foundayo showed bigger drops in A1C levels and weight compared to the competing drug.

Analysis

Lilly's orforglipron pill beat Novo's semaglutide pill on blood sugar and weight in three trials. That puts Lilly in a strong spot in the oral diabetes drug race.

  • Orforglipron (Foundayo) showed superior A1C control vs semaglutide pill in three pivotal type 2 diabetes trials
  • Foundayo also showed greater weight loss than the competing semaglutide pill
  • Data came from three separate pivotal trials per Eli Lilly press release
Eli Lilly Press Releases12d
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STAT+: Pharmalittle: We’re reading about Lilly and Pfizer obesity drug data, Roche and J&J deals, and more
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CLINICAL TRIAL

STAT+: Pharmalittle: We’re reading about Lilly and Pfizer obesity drug data, Roche and J&J deals, and more

Eli Lilly released new safety and side-effect data on retatrutide, its next-generation weight-loss drug. The data give doctors more details about how the drug works in patients.

Analysis

New safety data on Lilly's retatrutide gives doctors a clearer picture of the drug before it reaches later-stage trials.

  • Eli Lilly released new safety and side-effect data on retatrutide
  • Retatrutide is described as Lilly's next-generation weight-loss drug
STAT News — Pharma12d
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CLINICAL TRIAL · PRIMARY SOURCE2 outlets

Lilly's Foundayo (orforglipron), the only oral GLP-1 taken without food or water restrictions, was associated with significant weight loss in women at every stage of menopause

Eli Lilly's Foundayo (orforglipron), an oral weight-loss drug you can take with food or water, helped women lose significant weight in two trials. Women in perimenopause lost up to 30.4 pounds, and those past menopause lost up to 28.2 pounds.

Analysis

Orforglipron showed weight loss in women at all menopause stages. This expands the pool of patients Lilly can target with its oral GLP-1 pill.

  • Foundayo (orforglipron) can be taken without food or water restrictions
  • Women in perimenopause lost up to 30.4 pounds in trial data
  • Women past menopause lost up to 28.2 pounds
Eli Lilly Press Releases13d
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STAT+: Lilly shares safety, tolerability data on its next-gen obesity drug
DEVELOPING
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CLINICAL TRIAL

STAT+: Lilly shares safety, tolerability data on its next-gen obesity drug

Eli Lilly shared safety and tolerability data on retatrutide, its next-generation weight-loss drug, at the American Diabetes Association's annual meeting. The data shows how well the drug works and what side effects patients experienced during testing.

Analysis

Lilly's retatrutide safety data at a major medical meeting helps show if the drug is safe enough to move forward. Good results push it closer to market.

  • Lilly shared safety and tolerability data on retatrutide at the American Diabetes Association annual meeting
  • Retatrutide is Lilly's next-generation weight-loss drug
STAT News — Pharma14d
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CLINICAL TRIAL · PRIMARY SOURCE2 outlets

Lilly's triple agonist, retatrutide, drove substantial improvements in weight, A1C, knee osteoarthritis pain, and obstructive sleep apnea, demonstrating its remarkable potential to treat obesity and its complications

Eli Lilly's retatrutide, a triple-action weight-loss drug, helped people lose an average of 70 pounds over 80 weeks in a major trial. The drug also reduced joint pain and improved sleep problems in people with obesity and related conditions.

Analysis

Retatrutide cut weight, joint pain, and sleep problems in one trial. That makes Lilly's drug look stronger than current options for people with obesity plus other conditions.

  • Retatrutide is described as a triple agonist targeting weight and obesity complications
  • Average weight loss was ~70 pounds over 80 weeks in the trial
  • Trial covered A1C, knee osteoarthritis pain, and obstructive sleep apnea outcomes
Eli Lilly Press Releases14d
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DEVELOPING
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CLINICAL TRIAL · PRIMARY SOURCE

Lilly to present new data on Foundayo, Mounjaro and retatrutide at the American Diabetes Association's 86th Scientific Sessions, building toward a new era of choice in diabetes and obesity care

Eli Lilly will present new study results on Foundayo (an oral weight-loss and diabetes drug), Mounjaro, and retatrutide at a major diabetes conference. The Foundayo data showed it worked better than two competing pills for type 2 diabetes.

Analysis

Lilly is showing new data on three drugs at once. Foundayo beating rival pills for type 2 diabetes could help doctors choose it over competitors.

  • Lilly to present data on Foundayo, Mounjaro, and retatrutide at ADA's 86th Scientific Sessions
  • Foundayo data showed it worked better than two competing pills for type 2 diabetes
Eli Lilly Press Releases23d
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COMMERCIAL · PRIMARY SOURCE

Foundayo and Zepbound now covered for millions of Americans

Eli Lilly said CVS Caremark will start covering its weight-loss drugs Foundayo and Zepbound for millions of Americans starting in June and October. Eligible patients may pay only $25 per month for their medicine.

Analysis

Millions of Americans may soon pay just $25/month for Lilly's weight-loss drugs. Broader coverage through CVS Caremark means more patients can afford Zepbound and Foundayo.

  • CVS Caremark will cover Foundayo and Zepbound starting in June and October
  • Eligible patients may pay $25 per month for their medicine
Eli Lilly Press Releases23d
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Importance
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CLINICAL TRIAL · PRIMARY SOURCE

Foundayo (orforglipron), a once-daily pill taken without food or water restrictions, was associated with reduced body weight of up to 13% in adults 65 and older with obesity or overweight, in new analysis of ATTAIN-1/2

Eli Lilly's new weight-loss pill Foundayo helped older adults lose up to 13% of their body weight in a large trial. The drug is taken once daily without needing to avoid food or water first.

Analysis

Foundayo showed up to 13% weight loss in adults 65+ with obesity. This age group is a large, underserved market for Lilly's oral pill.

  • Foundayo (orforglipron) linked to up to 13% body weight reduction in adults 65 and older
  • Analysis drawn from ATTAIN-1 and ATTAIN-2 trials
  • Drug is taken once daily with no food or water restrictions
Eli Lilly Press Releases29d
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Lilly’s triple-acting obesity drug hits goal in Phase 3 trial
BREAKING
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CLINICAL TRIAL2 outlets

Lilly’s triple-acting obesity drug hits goal in Phase 3 trial

Eli Lilly's retatrutide, a weight-loss drug that works three different ways in the body, helped people in a major trial lose about one-quarter of their body weight. This result may be stronger than what competitors like Novo Nordisk have shown with their own weight-loss drugs.

Analysis

Retatrutide hit its Phase 3 goal with around 25% body weight loss. That may top Novo Nordisk's drugs and puts Lilly in a strong spot in the obesity market.

  • Retatrutide is described as a triple-acting obesity drug
  • Drug helped people lose about one-quarter of their body weight in Phase 3
  • Result described as potentially stronger than Novo Nordisk competitor drugs
BioPharma Dive1mo
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STAT+: Pharmalittle: We’re reading about a Lilly obesity drug trial, statistics for an Alzheimer’s drug, and more
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CLINICAL TRIAL

STAT+: Pharmalittle: We’re reading about a Lilly obesity drug trial, statistics for an Alzheimer’s drug, and more

Eli Lilly said its new obesity drug worked almost as well as weight-loss surgery in a late-stage trial. The company tested the drug on people struggling with weight to see if it could help them lose pounds.

Analysis

Lilly says a new obesity drug matched surgery results in a late trial. No trial details or drug name were confirmed in the source.

  • Lilly reported a new obesity drug performed nearly as well as weight-loss surgery in a late-stage trial
STAT News1mo
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BREAKING
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CLINICAL TRIAL · PRIMARY SOURCE

Lilly's triple agonist, retatrutide, delivered powerful weight loss in pivotal Phase 3 obesity trial

Eli Lilly's retatrutide, a new weight-loss drug that works three different ways, helped people lose an average of 70 pounds in a big Phase 3 trial. Nearly half of patients lost at least 30% of their body weight, which is as much as people usually lose from weight-loss surgery.

Analysis

Retatrutide's Phase 3 results show weight loss close to surgery levels. This puts Lilly ahead in the obesity drug race and pressures rivals like Novo Nordisk.

  • Retatrutide is described as a triple agonist in a pivotal Phase 3 obesity trial
  • Average weight loss was approximately 70 pounds in the trial
  • Nearly half of patients lost at least 30% of body weight
Eli Lilly Press Releases1mo
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STAT+: Lilly’s ‘triple-G’ drug leads to bariatric-surgery levels of weight loss in trial
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CLINICAL TRIAL

STAT+: Lilly’s ‘triple-G’ drug leads to bariatric-surgery levels of weight loss in trial

Eli Lilly's retatrutide (a three-hormone weight-loss drug) helped patients lose as much weight as bariatric surgery in a trial. However, some patients quit the study because of side effects.

Analysis

Lilly's retatrutide matched bariatric surgery weight loss in a trial. That is a big deal for people who can't or won't have surgery.

  • Retatrutide is a three-hormone weight-loss drug made by Eli Lilly
  • Trial results showed weight loss comparable to bariatric surgery
  • Some patients dropped out of the study due to side effects
STAT News1mo
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Lilly data point to ‘maintenance’ strategies for GLP-1 weight loss
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CLINICAL TRIAL

Lilly data point to ‘maintenance’ strategies for GLP-1 weight loss

Eli Lilly's trial data suggests that people losing weight on high-dose shot versions of its drug could switch to lower doses or pills and still keep the weight off. The findings point to cheaper, easier ways to maintain weight loss once someone has hit their goal.

Analysis

Lilly data suggest people could switch from costly high-dose shots to cheaper pills or lower doses and keep weight off. That widens how many patients can afford to stay on Lilly drugs long-term.

  • Lilly trial data suggest patients on high-dose injections may switch to lower doses or pills to maintain weight loss
  • Findings point to maintenance strategies after patients reach their weight-loss goal
BioPharma Dive1mo
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CLINICAL TRIAL · PRIMARY SOURCE

Lilly's Foundayo and lower-dose Zepbound helped people maintain weight loss after switching from higher doses of injectable incretin therapy in two late-phase trials

Eli Lilly released results from two late-stage trials showing that people who switched from higher-dose Wegovy or Zepbound to lower doses of Lilly's Foundayo pill or lower-dose Zepbound kept nearly all their weight loss over one year. The trials suggest the lower doses work well enough to maintain results when people switch from stronger versions.

Analysis

Lilly's pill Foundayo may let patients step down from high-dose shots and keep their weight off. That could pull patients away from Novo's Wegovy.

  • Two late-stage trials tested switching from higher-dose incretin therapy to lower doses
  • Patients switched to Foundayo pill or lower-dose Zepbound maintained weight loss over one year
  • Results came from Eli Lilly press releases, not yet peer-reviewed
Eli Lilly Press Releases1mo
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COMMERCIAL

Lilly’s Foundayo reached 7,335 prescriptions in week four, but trails Wegovy - mezha.net

Eli Lilly's Foundayo (tirzepatide pill) hit 7,335 prescriptions in its fourth week on the market. The new drug is selling slower than Novo Nordisk's Wegovy, a competing weight-loss injection.

Analysis

Lilly's new weight-loss pill is off to a slow start. Novo's Wegovy shot is still outselling it, so Novo keeps the lead in the obesity drug market.

  • Foundayo hit 7,335 prescriptions in its fourth week on the market
  • Foundayo is Lilly's tirzepatide pill
  • Foundayo is selling slower than Novo's Wegovy injection
Semaglutide News1mo
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BREAKING
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COMMERCIAL

Lilly's obesity pill tops 7,000 prescriptions in fourth week, signals modest uptake - Reuters

Eli Lilly's obesity pill reached 7,000 prescriptions in its fourth week on the market. The number suggests a slow start compared to competing weight-loss drugs.

Analysis

Lilly's new weight-loss pill is selling slower than hoped. That could give rivals like Novo more time to catch up in the pill race.

  • Lilly's obesity pill hit 7,000 prescriptions in its fourth week on the market
  • Uptake looks slow versus other weight-loss drugs
Reuters Health1mo
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Lilly, Gilead lead pharma’s M&A boom
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DEAL

Lilly, Gilead lead pharma’s M&A boom

Analysis

Lilly is spending GLP-1 drug profits on buyouts. Terns was bought by Merck, not a peptide play.

  • Lilly made 3 deals in 2026 with $10.8B total upfront payments, funded by GLP-1 drug revenue
  • Merck bought Terns Pharmaceuticals for its CML drug, not a peptide program
  • 24 pharma deals closed Jan–Apr 2026 vs 14 in same period 2025; upfront value: $64B vs $24.5B
BioPharma Dive1mo
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DEVELOPING
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COMMERCIAL

Lilly's Next Obesity Drug Is So Powerful It's Already Getting Copied - Investor's Business Daily

Eli Lilly's new obesity drug retatrutide is so effective that people are already making illegal copies of it. The drug hasn't even been fully approved yet, but compounding pharmacies are producing their own versions.

Analysis

Lilly's next weight-loss drug retatrutide is already being copied before approval. That could pull sales from Lilly and spark a new FDA fight over copycat pharmacies.

  • Lilly's obesity drug retatrutide is being copied before full approval
  • Compounding pharmacies are making their own versions of the drug
Retatrutide News1mo
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COMMERCIAL

Mounjaro Sales Exceed Keytruda in Q1 2026; Tirzepatide Sales Outpace Keytruda by $5 Billion in FY2025 - geneonline.com

Eli Lilly's tirzepatide (sold as Mounjaro for diabetes) brought in $5 billion more in sales than its cancer drug Keytruda in 2025. In early 2026, Mounjaro sales grew even larger and surpassed Keytruda's quarterly revenue.

Analysis

Lilly's tirzepatide is now its biggest drug, beating the old top seller Keytruda. This shows how huge the weight-loss and diabetes market has become.

  • Tirzepatide sales beat Keytruda by $5 billion in 2025
  • Mounjaro quarterly sales passed Keytruda in Q1 2026
  • Mounjaro is Lilly's tirzepatide brand for diabetes
Tirzepatide News1mo
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COMMERCIAL

GLP-1 Market to Reach $180 Billion by 2035 at 8.7% CAGR | Novo Nordisk, Eli Lilly, Pfizer Among Key Players - openPR.com

Analysis

A market report says GLP-1 drug sales could hit $180 billion by 2035. That points to years of strong growth for Novo and Lilly.

  • GLP-1 market projected to reach $180 billion by 2035
  • Forecast assumes 8.7% compound annual growth rate
  • Novo Nordisk, Eli Lilly, and Pfizer named as key players
Novo Nordisk News1mo
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COMMERCIAL

Lilly’s Mounjaro becomes world’s best-selling drug - Global Cosmetics News

Eli Lilly's Mounjaro (tirzepatide) is now the world's best-selling drug. The weight-loss and diabetes medicine has become more popular than all other drugs globally.

Analysis

Mounjaro is now the top-selling drug in the world. That puts Lilly ahead of Novo's Ozempic in the race to dominate weight-loss and diabetes care.

  • Mounjaro (tirzepatide) is now the world's best-selling drug
  • The drug treats both weight loss and diabetes
  • It has passed all other medicines in global sales
Tirzepatide News1mo
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COMMERCIAL

Retatrutide Black Market: Why Consumers Will Do Anything To Get Eli Lilly's New GLP - Investor's Business Daily

People are buying retatrutide, Eli Lilly's new weight-loss drug, on the black market because they can't get it through normal channels. The high demand shows how much people want the drug even before it's widely available.

Analysis

People want Lilly's next weight-loss drug so badly they are buying it illegally before it is even approved. That signals huge demand once it launches.

  • Retatrutide is Eli Lilly's experimental GLP weight-loss drug
  • Buyers are sourcing retatrutide on the black market
  • Drug is not yet available through normal channels
Retatrutide News1mo
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COMMERCIAL

Lilly Invests $4.5B to Indiana Manufacturing Site - PharmTech.com

Eli Lilly is spending $4.5 billion to build or expand a factory in Indiana. The investment likely supports production of tirzepatide (Mounjaro), Lilly's blockbuster weight-loss and diabetes drug.

Analysis

More factory space means Lilly can make more Mounjaro and Zepbound. That helps ease the ongoing shortage of weight-loss shots.

  • Eli Lilly is spending $4.5 billion on an Indiana manufacturing site
  • The investment supports tirzepatide (Mounjaro) production
Tirzepatide News1mo
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COMMERCIAL

Eli Lilly’s Mounjaro Becomes World’s Top-Selling Drug - The Business of Fashion

Eli Lilly's tirzepatide (Mounjaro) is now the best-selling drug in the world. The drug treats both diabetes and weight loss, and its sales have grown faster than any other medicine.

Analysis

Mounjaro is now the top-selling drug in the world. That shows how fast weight-loss and diabetes shots are taking over the drug market.

  • Eli Lilly's Mounjaro (tirzepatide) is now the world's top-selling drug
  • The drug treats both diabetes and weight loss
  • Sales have grown faster than any other medicine
Tirzepatide News1mo
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Novo Nordisk CEO following Eli Lilly's entry into the tablet market: "I am quite confident" - medwatch.com

Analysis

Novo's CEO says he is not worried about Lilly's new weight-loss pill. The two drugmakers are racing to win the pill market, not just shots.

  • Novo Nordisk's CEO said he is 'quite confident' about the pill market.
  • Eli Lilly has entered the tablet (oral) weight-loss drug market.
  • Comments come as both firms compete in oral GLP-1 drugs.
Novo Nordisk News1mo
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